Florence, Italy
5-9 May 2012

Scientific Programme

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5 May 2012
08:00 17:00  Pre-Congress Course: Proper Medical Writing
For the full programme and to register for your place on this course, please visit the Medical Writing Course section on this website by clicking on the session title above.
Location: Magnolia
09:00 17:00  Insights Into Italian Endocrinology and Metabloism
For further information see http://web.aimgroupinternational.com/2012/sie/
09:00 17:00  Pre-Congress Course: Thyroid Ultrasound
For the full programme, please visit the Thyroid Ultrasound Course section on this website by clicking on the session title above.
Location: Sherma
12:00 20:00  Registration
Location: Padiglione Centrale
15:00 17:00  SANDOZ Satellite Symposia - Maturing metabolism: A neurondocrine affair
Chair(s): G. Stalla (Germany ) & T. Brue (France)
Location: Basilica
15:00Chairman's Welcome
G. Stalla & T. Brue (Germany & France)
   
15:10Searching in the wrong place: The endocannabinoid system revisited
U. Pagotto (Italy)
   
15:35Metabolic control: It's a gut feeling
P.T. Pfluger (Germany)
   
16:00Endocrine regulation of lifespan: Lessons from the animal models
J. Kopchick (USA)
   
16:25Looking for longevity: Look in your genes
S. Lamberts (The Netherlands)
   
16:50Closing remarks
G. Stalla (Germany) & T. Brue (France)
   
15:30 17:30  Emerging issues in Scientific Publishing: A Round Table Event
Teatrino
1. Search for reviewers - a difficult task for editors
   
2. Rebuttal of negative editor's decision by authors and the immediate rejection of a paper: how to minimise the risk
   
3. Conflict of interest: what really needs to be declared
   
4. The H - index: why so mancy variables and how to discern
   
5. Ethical issues (duplication, plagiarism, conflict of interest)
   
6. Perspective for Journals in the Endocrine and Metabolic field
   
17:30 19:30  ICE/ECE 2012 Opening Ceremony: Welcome & introduction
Main Lecture Hall
Chairs: Chair(s): F. Casanueva, ISE President (Spain) & P. Bouchard, ESE President (France)
17:30Welcome to Florence & ICE/ECE 2012
M. Reincke & G. Forti (Germany & Italy)
   
17:45Welcoming addresses
Invited guests
   
17:55 18:40  Geoffrey Harris Prize Lecture
Main Lecture Hall
Chairs: Chair(s): P. Bouchard (France) & J. Castano (Spain)
17:55GH1Glucocorticoid metabolism and the brain, from fetal programming to senescence
J. Seckl (UK)
   
18:45 19:30  European Journal of Endocrinology Prize Lecture
Main Hall
Chair: Chair(s): J. Romijn - Editor-in-Chief of EJE (The Netherlands)
18:45EJE1Tacklling obesity: lessons from genetics
S. Farooqi (UK)
   
19:30 21:00  ICE/ECE 2012 Welcome Reception
Generously Supported by Florence Convention Bureau
Sponsored by Endocrine Connections
Exhibition Hall
6 May 2012
07:00 20:00  Registration
08:30 09:15  Plenary Lecture 1
Location: Main Hall
Chair: Chair(s): E. Nieschlag (Germany)
08:30PL1Red wine endocrinology
D. Sinclair (USA)
   
09:15 09:25  Presidents' Address
P. Bouchard (France) & F Casanueva (Spain)
09:30 11:00  Symposium 1: Molecular mechanisms of differentiated thyroid cancer
Location: Main Hall
Chairs: Chair(s): R. Elisei (Italy) & B. Jarzab (Poland)
09:30S1.1Molecular consequences of deregulated microRNAs in papilliary thyroid carcinoma
A. de la Chapelle (USA)
   
10:00S1.2Correlation between the BRAF V600E mutation; TGF beta pathway and tumour invasiveness in papillary thyroid carcinoma
P. Santistebar (Spain)
   
10:30S1.3Molecular genotyping of papillary thyroid carcinoma
M. Sobhrino-Simoes (Portugal)
   
09:30 11:00  Symposium 2: 40 years of male hormonal contraception research and no product
Location: Hall A
Chairs: Chair(s): E. Nieschlag (Germany) & F. Wu (UK)
09:30S2.1Do we know enough about regulation of testicular function?
R. McLachlan (Australia)
   
10:00S2.2Clinical trials in male hormonal contraception to date
C. Meriggiola (Italy)
   
10:30S2.3Acceptability of male hormonal contraception by the pharmaceutical industry and by the consumer
F. Saad (Germany)
   
09:30 11:00  Symposium 3: Absolute fracture risk assessment with FRAX
Location: Hall B
Chairs: Chair(s): F. Cetani (Italy) & R. Rizzoli (Switzerland)
09:30S3.1Overview of FRAX
J. Kanis (UK)
   
10:00S3.2Use of FRAX in Asian populations
L. Koh (Singapore)
   
10:30S3.3Beyond FRAX
J. Eisman (Australia)
   
09:30 11:00  Symposium 4: The gut nutrient sensing in energy metabolism
Location: Hall C
Chairs: Chair(s): H. Itoh (Japan) & C. Rotella (Italy)
09:30S4.1Bile acid metabolism for the control of metabolic disease
M. Watanbe (Japan)
   
10:00S4.2Taste receptors in gut regulate endocrine function
R. Margolskee (USA)
   
10:30S4.3Gut microbiome and energy metabolism: The concept of micro-obesity
P. Cani (Belgium)
   
09:30 11:00  Symposium 5: Transition from paediatric to adult care - do we have progress?
Location: Hall D
Chairs: Chair(s): C. Hoybye (Sweden) & P. Garofalo (Italy)
09:30S5.1Prader-Willi syndrome childhood and adult life: Outcome report from a consensus workshop
C. Deal (Canada)
   
10:00S5.2 Fertility options for young adults with panhypopituitarism
M. Wierman (USA)
   
10:30S5.3Sex steroid replacement in young males and females
G. Conway (UK)
   
09:30 11:00  Symposium 6: Subclinical adrenal diseases
Location: Hall E
Chairs: Chair(s): A. Lacroix (Canada) & E. Husebye (Norway)
09:30S6.1Diagnosis and treatment of subclinical Cushing's syndrome (SCS)
T. Yanase (Japan)
   
10:00S6.2Silent phaeochromocytoma
R. Clifton-Bligh (Australia)
   
10:30S6.3Subclinical Addison's disease
A. Falorni (Italy)
   
09:30 11:00  Symposium 7: Hormones, metabolism and cancer: more than coincidences?
Location: Hall F
Chairs: Chair(s): C. Strasberger (Germany) & A. Dunaif (USA)
09:30S7.1An epigenetic switch linking inflammation to cancer and the use of metaformin as an anti-cancer drug
K. Struhl (USA)
   
10:00S7.2The insulin-like growth factor system and cancer: What are the implications?
D. Le Roith (USA)
   
10:30S7.3Obesity and cancer
A. Renehan (UK)
   
09:30 11:00  Symposium 8: Global phenotypes of endocrine disease
Location: Hall G
Chairs: Chair(s): P. Bouchard (France) & B. Allolio (Germany)
09:30S8.1Vitamin D deficiency in Asia
G. El-hajj Fuleihan (Lebanon)
   
10:00S8.2Ethnic specific PCOS
C. Wijeyaratne (Sri Lanka)
   
10:30S8.3TBC
TBC
   
09:30 11:00  Symposium 9: The risk and benefits of tight glycaemic control
Location: Hall H
Chairs: Chair(s): S. del Prato (Italy) & W. Sheu (Taiwan)
09:30S9.1What do type 2 diabetes outcome trials tell us about the cardiovascular risks and benefits of intensive glycaemic control?
H. Gerstein (Canada)
   
10:00S9.2Tight control of blood glucose levels in the hospitalised patient
M. Korytkowski (USA)
   
10:30S9.3Time course of the glucose legacy effect
R. Holman (UK)
   
11:00 11:30  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
11:30 12:30  Debate 1: This house believes that metabolic (bariatric) surgery should be offered to every diabetic with a BMI over 30
For: G. Mingrone (Italy); Against: E. Mannucci (Italy)
Location: Main Hall
Chair: Chair(s): V. Pirags (Latvia)
11:30 12:15  Meet the Expert 1
Location: Hall A
11:30MTE1Adrenal incidentaloma and subclinical Cushing's syndrome
P. Stewart (UK)
   
11:30 12:15  Meet the Expert 2
Location: Hall B
11:30MTE2Approach to the patient with Cushing's disease after pituitary surgery failure
M. Toth (Hungary)
   
11:30 12:15  Meet the Expert 3
Location: Hall C
11:30MTE3Osteoporosis in men
U. Gruntmanis (USA)
   
11:30 12:15  Meet the Expert 4
Location: Hall D
11:30MTE4Challenges of transsphenoidal pituitary surgery
P. Cappabianca (Italy)
   
11:30 12:15  Meet the Expert 5
Location: Hall E
11:30MTE5Discussion of common but difficult thyroid cancer cases
L. Wartofsky (USA)
   
11:30 12:15  Meet the Expert 6
Location: Hall F
11:30MTE6Clinical management of adrenocortical carcinoma
M. Terzolo (Italy)
   
11:30 12:15  Meet the Expert 7
Location: Hall G
11:30MTE7Pregnancy and pituitary disorders
Z. Karaca (Turkey)
   
11:30 12:15  Meet the Expert 8
Location: Hall H
11:30MTE8Diagnosis and treatment of precocious puberty
L. Ghizzoni (Italy)
   
12:25 13:10  Meet the Expert 9
Location: Hall A
12:25MTE9Diagnosis and treatment of SIADH
C. Thompson (Ireland)
   
12:25 13:10  Meet the Expert 10
Location: Hall B
12:25MTE10Elastosonography in the evaluation of thyroid and parathyroid lesions
M. Erdogan (Turkey)
   
12:25 13:10  Meet the Expert 11
Location: Hall C
12:25MTE11Diagnosis and treatment considerations in autoimmune polyendocrine syndrome
O. Kampe (Sweden)
   
12:25 13:10  Meet the Expert 12
Location: Hall D
12:25MTE12Goitre throughout the paediatric ages
M. Polak (France)
   
12:25 13:10  Meet the Expert 13
Location: Hall E
12:25MTE13Graves' ophthalmopathy
W. Wiersinga (The Netherlands)
   
12:25 13:10  Meet the Expert 14
Location: Hall F
12:25MTE14Hirsutism
K. Unluhizarci (Turkey)
   
12:25 13:10  Meet the Expert 15
Location: Hall G
12:25MTE15Pituitary tumours in adolescents and adults
M. Andersen (Denmark)
   
12:25 13:10  Meet the Expert 16
Location: Hall H
12:25MTE16Management of non-functioning pituitary adenomas
N. Karavitaki (UK)
   
12:30 13:15  Lunch, Posters & Exhibition
ESE President meets ESE Affiliated Society Presidents (invitation only)
Exhibition Hall & Poster Hall
13:15 14:45  Symposium 10: Thyroid: From fetal life to adulthood
Location: Hall A
Chairs: Chair(s): K. Brix (Germany) & S. Gullu (Turkey)
13:15S10.1Placental transport of thyroid hormone
S. Chan (UK)
   
13:45S10.2Importance of fetal life for adult thyroid disease
R. Gartner (Germany)
   
14:15S10.3Thyroid hormones and fetal neurological development
M. Li (Australia)
   
13:15 14:45  Symposium 11: Novel genetic and endocrine insights in the Klinefelter's syndrome
Location: Hall B
Chairs: Chair(s): K. Kula (Poland) & R. Swerdloff (USA)
13:15S11.1Klinefelter mouse (47XXY): Model for human klinefelter syndrome
R. Swerdloff (USA)
   
13:45S11.2Endocrine changes in klinefelter's syndrome and the effects on growth, bone and body composition
L. Aksglaede (Denmark)
   
14:15S11.3The Muenster EXAKT project: Epigenetic regulation of the supernumerary X chromosome and its escape genes
J. Gromoll (Germany)
   
13:15 14:45  Symposium 12: Determinants of peak bone mass
Location: Hall C
Chairs: Chair(s): R. Prince (Australia) & K. Brixen (Denmark)
13:15S12.1Epidemiology of peak bone mass, structure and strength in males as assessed by high resolution peripheral quantitative CT (HR-pQCT). A cross-sectional study.
K. Brixen (Denmark)
   
13:45S12.2The contribution of genetic factors to bone mass
W. van Hul (Belgium)
   
14:15S12.3Estrogens as regulators of bone growth and bone mass
C. Ohlsson (Sweden)
   
13:15 14:45  Symposium 13: Novel therapies for protecting beta cell function at diagnosis of type 1 diabetes
Location: Hall D
Chairs: Chair(s): I. Satman (Turkey) & R. Buzzetti (Italy)
13:15S13.1Therapy with anti-CD3 monoclonal antibody
R. Buzzetti (Italy)
   
13:45S13.2Peptide therapy (Diapepe277)
R. Itamar (Israel)
   
14:15S13.3Therapy with glutamic acid decarboxylase (GAD)
J. Ludvigsson (Sweden)
   
13:15 14:45  Symposium 14: Wnt/Beta-catenin in pituitary development and disease
Location: Hall E
Chairs: Chair(s): A. Spada (Italy) & G. Stalla (Germany)
13:15S14.1Wnt/Beta-catenin in pituitary development
S. Camper (USA)
   
13:45S14.2Wnt/Beta-catenin signalling in craniopharyngioma
J.P. Martinez-Barbera (UK)
   
14:15S14.3Wnt signalling in oestrogen induced lactotroph proliferation
J. Davis (UK)
   
13:15 14:45  Symposium 15: Adrenal cancer
Location: Hall F
Chairs: Chair(s): B. Skogseid (Sweden) & V. Toscano (Italy)
13:15S15.1Molecular pathogenisis of adrenocortical cancer
E. Lalli (France)
   
13:45S15.2Imaging of adrenocortical cancer
I. Ilias (Greece)
   
14:15S15.3Genetics of micronodular hyperplasias (associated with Cushing syndrome)
C. Stratakis (USA)
   
13:15 14:45  Symposium 16: Understanding growth
Location: Hall G
Chairs: Chair(s): F. Minuto (Italy) & M. Andersen (Denmark)
13:15S16.1From Galton to GWAS (and beyond): what we have learned about the genetics of human height?
P. Visscher (Australia)
   
13:45S16.2Genes and the investigation of idiopathic short stature (ISS): are we ready for prime time?
J-M. Wit (The Netherlands)
   
14:15S16.3What is the optimal growth of small gestational age (SGA) babies: lessons from WHO?
S. Chernausek (USA)
   
13:15 14:45  Symposium 17: Hormonal control of pregnancy
Location: Hall H
Chairs: Chair(s): G. Bartfai (Hungary) & Z. Karaca (Turkey)
13:15S17.1Hormone signalling between mother and foetus
R. Reynolds (UK)
   
13:45S17.2What controls labour in humans?
R. Smith (Australia)
   
14:15S17.3Placental hormones as putative markers of gestational diseases
F. Petraglia (Italy)
   
14:45 15:15  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
15:15 16:45  Symposium 18: Molecular mechanisms in autoimmune thyroid disease
Location: Hall A
Chairs: Chair(s): M. Tonacchera (Italy) & M. Marazuela (Spain)
15:15S18.1Predictors of relapse of Graves' disease after antithyroid drug withdrawal
P-W. Wang (Taiwan)
   
15:45S18.2Genotype-phenotype correlations in Grave's disease
T. Bednarczuk (Poland)
   
16:15S18.3Regulatory cells, Th17 lymphocytes, and dendritic cells in autoimmune thyroid disease
M. Marazuela (Spain)
   
15:15 16:45  Symposium 19: Controversies in testosterone replacement
Location: Hall B
Chairs: Chair(s): J-M. Kaufman (Belgium) & R. Legro (Italy)
15:15S19.1Can we really measure testosterone?
R. Legro (USA)
   
15:45S19.2Late onset hypogonadism - who should receive testosterone?
J. Svartberg (Norway)
   
16:15S19.3Testosterone for women: why, when and how?
S. Davis (Australia)
   
15:15 16:45  Symposium 20: Signalling to and from osteoclasts
Location: Hall C
Chairs: Chair(s): J. Bollerslev (Norway) & X. Cao ( USA)
15:15S20.1Efferent signalling by osteoclasts
K. Matsuo (Japan)
   
15:45S20.2Immune signalling in osteoclasts
H. Takayanagi (Japan)
   
16:15S20.3TGF beta brings osteoclasts to sites of resorbtion
X. Cao (USA)
   
15:15 16:45  Symposium 21: Obesity and reproduction
Location: Hall D
Chairs: Chair(s): M. Tena-Sempere (Spain) & R. Pasquali (Italy)
15:15S21.1Integrating hypothalamic regulation of energy homeostasis and reproduction
C. Elias (USA)
   
15:45S21.2Impact of obesity on male reproduction
A.C. Martini (Argentina)
   
16:15S21.3Lifestyle modification and fertility
R. Norman (Australia)
   
15:15 16:45  Symposium 22: Pituitary tumourigenesis
Location: Hall E
Chairs: Chairs: I. Huhtaniemi (UK) & L. Hofland (The Netherlands)
15:15S22.1Molecular mechanisms: the genes involved in pituitary tumorigenesis
S. Melmed (USA)
   
15:45S22.2Tracing back a gene's influence
M. Korbonits (UK)
   
16:15S22.3Pituitary tumourigenesis
A. Daly (Belgium)
   
15:15 16:45  Symposium 23: Advances in regulation of aldosterone synthesis
Location: Hall F
Chairs: Chair(s): H. Shibata (Japan) & F. Beuschlein (Germany)
15:15S23.1Regulation of aldosterone synthase expression in normal adrenal and primary aldosteronism
W. Rainey (USA)
   
15:45S23.2Extra-adrenal aldosterone biosynthesis
C. Gomez-Sanchez (USA)
   
16:15S23.3Role of N-type calcium channel blockers in aldosterone biosynthesis
M. Yoshimura (Japan)
   
15:15 16:45  Symposium 24: Diabetes in children
Location: Hall G
Chairs: Chair(s): M. Craig (USA) & F. Amara (Egypt)
15:15S24.1Epidemiology of ketoacidosis: Can we influence the incidence
H. Bui (Canada)
   
15:45S24.2Hypotheses explaining the increase in type 1 diabetes
M. Knip (Finland)
   
16:15S24.3Type 2 diabetes in children
M. Craig (Australia)
   
15:15 16:45  Symposium 25: Reproductive hormone action
Location: Hall H
Chairs: Chair(s): TBC & J. Gromoll (Germany)
15:15S25.1GnRH receptor signalling
U. Kaiser (USA)
   
15:45S25.2Light on the structural communication in gonadotrophin hormone receptors: implications in genetic diseases
F. Fanelli (Italy)
   
16:15S25.3Extragonadal follicle stimulating hormone action - facts and dreams
N. Ghinea (France)
   
17:00 17:45  Plenary Lecture 2
Location: Main Hall
Chair: Chair(s): G. Forti (Italy)
17:00PL2Testosterone - More than sex
M. Maggi (Italy)
   
17:45 18:00  In Memoriam
Location: Main Hall
Chairs: Chair(s): P. Bouchard (France) & F. Casaneuva (Spain)
18:00 19:30  Poster Reception
Attended poster session, refreshments available
Poster Hall
18:30 20:00  VIROPHARMA Satellite Symposia - Challenges of glucocorticoid replacement therapy in adrenal insufficiency
Location: Teatrino
Chair: B.M.K. Biller
18:30Introduction
B.M.K. Biller
   
18:40Management of Addison's disease, why are we failing our patients
P.M. Stewart
   
19:00Stress response and prevention of adrenal crisis in chronic adrenal insufficiency
S.S. Hahner
   
19:20Difficult cases such as pregnancy and concomittant type 1 diabetes mellitus
J.P. Monsson
   
19:40The cortisol concentration time profile and metabolic outcome
G. Johannsson (Sweden)
   
19:55Closing remarks
B.M.K. Biller
   
18:30 20:00  ALEXION PHARMACEUTICALS Satellite Symposia - Uncommon causes of fractures: Differential diagnosis and innovative treatment options
Location: Hall H
Chair: Chair(s): M.L. Brandi
18:30Introduction & Welcome
M.L. Brandi
   
18:35Review Skeletal Mineralization
M.L. Brandi
   
18:50Paget's Disease
L. Gennari
   
19:10Osteoporosis
R. Eastell
   
19:30Hypophosphatasia
C. Kasperk
   
19:50Q&A and Closing Remarks
M.L. Brandi
   
18:30 20:00  IBSA Satellite Symposia - Therapy of hypothyroidism: adult and child confronted. Experiences with levothyroxine in oral solution
Location: Hall F
Chairs: Chair(s): P. Vitti (Pisa, Italy) & M. Cappa (Rome, Italy)
18:15Welcome and introduction
M. Cappa (Rome, Italy)
   
18:20Pharmacokinetics of L-thyroxine in oral solution vs solid dosage forms
M.P. Ducharme (Canada)
   
18:35L-thyroxine: more oral forms for a fine individual dose calibration
M. Centanni & S. Benvenge (Rome & Messina, Italy)
   
19:05Therapy of congenital hypothyroidism: the experience of two Italian centres with liquid L-thyroxine
A. Cassio & G. Weber (Italy & Italy)
   
19:35Discussion
P. Vitti (Pisa, Italy)
   
19:45End of session
   
18:30 20:00  OTSUKA Satellite Symposia - Head to head in hyponatraemia: Comparing clinical approaches
Location: Hall G
Chair: J. Verballs (USA)
18:30Welcome: What is your hyponatraemia mind-set?
J. Verballs (USA)
   
18:35Everyday issues in hyponatraemia: What would you do?
J. Verballs (USA)
   
18:55Applying clinical data to real-life decisions on hyponatraemia management: Experience from the front line
Case 1 - Comprehensive diagnosis
A. Peri (Italy)
   
19:20Applying clinical data to real-life decisions on hyponatraemia management: Experience from the front line
Case 2 - Optimising treatment
C. Thompson (Ireland)
   
19:45Revisiting our hyponatraemia patients: has the mind-set changed?
J. Verballs (USA)
   
19:55Questions & Answers
   
18:30 20:00  PFIZER Satellite Symposia - Metabolic Consequences of Medical Treatment for Acromegaly
Location: Hall A
Chairs: Chair(s): Ezio Ghigo (Italy) & Christian Strasburger (Germany)
18:30Clinical significance of metabolic perturbations in acromegaly
K. Ho (Australia)
   
18:50Body composition and lipid changes during the treatment of acromegaly
P. Chanson (France)
   
19:10Differential effects on glycaemia of SSAs (old & new) vs Pegvisomant
W. Drake (UK)
   
19:30Ever heard of extra-hepatic acromegaly?
A.J. van der Lely (The Netherlands)
   
20:30 00:00  ICE/ECE 2012 Congress Dinner
Tickets should be purchased during registration
Palazzo Corsini
7 May 2012
07:00 20:00  Registration
08:30 09:15  Plenary Lecture 3
Location: Main Hall
Chair: Chair(s): M. Reincke (Germany)
08:30PL3Mating, sex and the immune system in humans and fish
M. Milinski (Germany)
   
09:30 11:00  Oral Communication Session 1 - Pituitary Clinical I
Location: Hall A
Chairs: Chair(s): M. Marazuela (Spain) & P. Burman (Sweden)
09:30OC1.1Pasireotide LAR is significantly more effective than octreotide LAR at inducing biochemical control in patients with acromegaly: results of a 12-month randomized, double-blind, multicenter, Phase III study
A-M. Colao (Italy)
   
09:45OC1.2Patients with Cushing’s disease achieve normal urinary cortisol with LCI699, a potent 11β-hydroxylase inhibitor: preliminary results from a multicenter, proof-of-concept study
X. Bertagna (France)
   
10:00OC1.3Efficacy and safety of long-term treatment with pegvisomant in acromegaly: Italian pegvisomant observational study (acrostudy)
A. Bianchi (Italy)
   
10:15OC1.4A multi-centre audit of the prevalence of cardiac valvulopathy in patients treated with dopamine agonists for hyperprolactinaemia
W. Drake (UK)
   
10:30OC1.5Initial hypothalamic involvement is the major risk factor for impaired prognosis and quality of life in childhood craniopharyngioma regardless of chosen treatment strategies – Results of KRANIOPHARYNGEOM 2000
H. Müller (Germany)
   
10:45OC1.6Normal weight adult patients with Prader-Willi syndrome are not protected from insulin resistance during treatment with growth hormone: Results from a 12 month prospective study
A. Jørgensen (Norway)
   
09:30 11:00  Oral Communication Session 2 - Thyroid Clinical I
Location: Hall B
Chairs: Chair(s): L. Bartalena (Italy) & I. Al-Ibrashy (Egypt)
09:30OC2.1Overt hyperthyroidism is associated with increased mortality. A nationwide register-based study of disease discordant Danish twins
F. Brandt (Denmark)
   
09:45OC2.2Identification and functional analysis of DUOX2 variants: Bialleclic mutations are associated with permanent congenital hypothyroidism
M. Muzza (Italy)
   
10:00OC2.3Thyroid hormone levels in euthyroid young men are associated with body composition and metabolic parameters
G. Roef (Belgium)
   
10:15OC2.4The thyroid hormone receptor-coactivator interface mediates negative feedback regulation of the human pituitary-thyroid axis
C. Moran (UK)
   
10:30OC2.5Thyroid spongiform nodules are the best candidates for percutaneous laser ablation. A 5 year follow-up study in 72 patients
G. S. Bortolani (Italy)
   
10:45OC2.6Concurrent presence of nonendocrine autoimmune diseases with Hashimoto's thyroiditis: A systematic assessment on more than 5000 consecutive patients
M. Cetanni (Italy)
   
09:30 11:00  Oral Communication Session 3 - Diabetes Clinical
Location: Hall C
Chairs: Chair(s): V. Pirags (Latvia) & K. Abdalla (Egypt)
09:30OC3.1Common variants of monogenic diabetes genes may affect beta cell functional mass in patients with newly diagnosed type 2 diabetes
S. Bonetti (Italy)
   
09:45OC3.2Weight-loss independent metabolic benefits of gastric bypass surgery? Experiences from the Swedish Obese Subjects (SOS) study
M. Peltonen (Finland)
   
10:00OC3.3Diabetic ketoacidosis at diagnosis influences complete remission after treatment of hematopoietic stem cell transplantation in adolescents with type 1 diabetes
W. Gu (China)
   
10:15OC3.4Glucose lowering therapies and cancer specific mortality in adult insulin-treated diabetes
S. Loacara (Romania)
   
10:30OC3.5Study of toll like receptor 2 and 4 expression in monocytes in type 1 diabetes mellitus with and without micro-vascular complications
R. Abd El Baki (Egypt)
   
10:45OC3.6Glucose disorders exert a detrimental effect on total brain volume in the elderly: a 2-year prospective MRI study
K. Samaras (Australia)
   
09:30 11:00  Oral Communication Session 4 - Pituitary Basic
Location: Hall D
Chairs: Chair(s): L. Hofland (The Netherlands) & M. Theodoropoulou (Germany)
Blank Abstract
   
09:30OC4.1Obestatin plays an opposite role in the regulation of pituitary somatotrope and corticotrope function in primates and mice
R. Luque (Spain)
   
09:45OC4.2Transcriptional regulation of prolactin by oestrogen in vivo.
A. Patist (UK)
   
10:00OC4.3miR-26a targets PRKCD in ACTH pituitary adenoma
E. Gentilin (Italy)
   
10:15OC4.4Identification of coupling specificity between somatostatin receptor 5 (SST5) and G proteins by a bioluminescence resonance energy transfer (BRET) technique: the role of GoA protein
E. Peverelli (Italy)
   
10:30OC4.5Targeting the IGF-IR system in pituitary tumors in vitro: antiproliferative action & pitfalls
M. Theodoropoulou (Germany)
   
10:45OC4.6Cell cycle G2/M transition is modulated by microRNAs in pituitary adenomas
H. Butz (Hungary)
   
09:30 11:00  Oral Communication 5 - Obesity Basic
Location: Hall E
Chairs: Chair(s): J. Gimble (USA) & S. Farooqi (UK)
09:30OC5.1Growth hormone ameliorates impaired glucose tolerance in obese mice by modifying the visceral fat condition through adiponectin
Y. Okamoto (Japan)
   
09:45OC5.2Production of galectin-1, -3, -9 and -12 in adipose tissue of lean and obese mice
G. Fantuzzi (United States)
   
10:00OC5.3Insulin action in brown adipose tissue is compromised during diet-induced obesity
C. Quarta (Italy)
   
10:15OC5.4Bile acid binding resin shows anti-obese effect through the modifications of intestinal microbiota
Y. Kusumoto (Japan)
   
10:30OC5.5Development of leptin deficient rat - evidence for its superiority over mouse as a model for human obesity
M. Aizawa-Abe (Japan)
   
10:45OC5.6Semaphorin 3C-a novel adipokine modulating human adipose tissue plasticity in weight change
M. Rydén (Sweden)
   
09:30 11:00  Oral Communication Session 6 - Female Reproduction Basic
Location: Hall F
Chairs: Chair(s): C. Elias (USA) & M. Simoni (Italy)
09:30OC6.1GnRH release failure in hyperprolactinemia is caused by a kisspeptin deficiency
N. Binart (France)
   
09:45OC6.2Ghrelin modulates fertilization, early embryo development and implantation
A. Martini (Argentina)
   
10:00OC6.3LH and hCG produce different responses in human granulosa lutein cells in vitro.
L. Casarini (Italy)
   
10:15OC6.4Female fertility and activin-stimulated Fshb expression do not require SMAD2/3 in murine gonadotropes
J. Fortin (Canada)
   
10:30OC6.5Dihydrotestosterone treatment in mice induces a persistent polycystic ovary syndrome phenotype
E. van Houten (The Netherlands)
   
10:45OC6.6Kit ligand-c-kit interaction regulates estradiol production by rat granulosa cells via oocyte factors
T. Miyoshi (Japan)
   
09:30 11:00  Oral Communication Session 7 - Adrenal Clinical
Location: Hall G
Chairs: Chair(s): B. Allolio (Germany) & J. Newell-Price (UK)
09:30OC7.1Progression-free survival without treatment of malignant pheochromocytoma and paraganglioma at one year
S. Hescot (France)
   
09:45OC7.2Activation of the PKA pathway triggers formation of an illicit serotonergic regulatory loop in primary pigmented nodular adrenal disease (PPNAD) tissues associated with Cushing’s syndrome
Z. Bram (France)
   
10:00OC7.3Ribonucleotide reductase large subunit (RRM1) gene expression predicts efficacy of adjuvant mitotane in adrenocortical cancer
M. Volante (Italy)
   
10:15OC7.4Differential diagnosis of primary aldosteronism by peripheral plasma levels of 18-oxo-cortisol - a noninvasive method with a high specificity
F. Satoh (Japan)
   
10:30OC7.5Continuous subcutaneous hydrocortisone infusion as replacement therapy in Addison’s disease
M. Øksnes (Norway)
   
10:45OC7.6Progressively increased patterns of subclinical cortisol hypersecretion in adrenal incidentalomas differently predict major metabolic and cardiovascular outcomes: a large cross-sectional study
G. Di Dalmazi (Italy)
   
09:30 11:00  Oral Communication Session 8 - Bone
Location: Hall H
Chair: Chair(s): C. Marcocci (Italy)
09:30OC8.1Hypophosphatasia: Enzyme replacement therapy (ENB-0040) decreases TNSALP substrate accumulation and improves functional outcome in affected adolescents and adults
N. Kreher (USA)
   
09:45OC8.2Comparison of high protein and normal protein weight loss diets on bone density in overweight post-menopausal women
D. Jesudason (Australia)
   
10:00OC8.3Profiling insulin like factor 3 (INSL3) signaling in human osteoblasts
A. Ferlin (Italy)
   
10:15OC8.4Radiological vertebral fractures in hospitalized elderly patients with heart failure
G. Mazziotti (Italy)
   
10:30OC8.5Pathogenetic chromosomal rearrangements in a large series of patients with pseudohypoparathyroidism type I
F. Marta Elli (Italy)
   
10:45OC8.6Simultaneous gain and loss of methylation at imprinted loci in a subset of patients with pseudohypoparathyroidism type 1b and GNAS epimutations
A. Linglart (France)
   
09:30 11:00  Oral Communication 9 - Endocrine Tumours & Translation
Location: Basilica
Chairs: Chair(s): K. Oberg (Sweden) & A. Grossman (UK)
09:30OC9.1Temozolomide therapy for progressive metastatic paraganglioma/pheochromocytoma: SDHB mutation as a prognosis biomarker for efficacy
J. Hadoux (France)
   
09:45OC9.2Growth hormone protects breast cancer cells from chemotherapy by blocking cytotoxic-induced apoptosis in estrogen receptor negative breast cancer cells
M. Minoia (Italy)
   
10:00OC9.3The central role of estrogen receptor α in IGF-II dependent adrenocortical carcinoma (ACC) cell proliferation suggests the use of selective estrogen receptor modulators (SERMs) for the treatment of ACC
V. Pezzi (Italy)
   
10:15OC9.4Functional characterization of mutations in the multiple endocrine neoplasia type 1 (MEN1) gene suggest therapeutic strategies
G. Hendy (Canada)
   
10:30OC9.5Glucagon-like peptide 1 receptor (GLP-1R) imaging for the preoperative localization of benign insulinomas in 30 patients
E. Christ (Switzerland)
   
10:45OC9.6First in vitro study of human gastroenteropancreatic-neuroendocrine tumors: Comparative effect of octreotide and pasireotide
A. Mohamed (France)
   
09:30 11:00  Endocrine Nurses' Session: Puberty Induction and Sex Steroid Replacement in Young Adults
Generously Supported By Novartis
Location: Polveriera
Chairs: Chair(s): J. Foote (USA) & P. Bouchard (France)
09:30EN1.1Puberty induction in males and females
C. Brain (UK)
   
10:00EN1.2The role of the endocrine nurse in puberty induction
M. Keil (USA)
   
10:15EN1.3Sex steroid replacement in young males and females
G. Conway (UK)
   
10:45EN1.4Choosing the right sex steroid replacement option for patients: the role of the endocrine nurse
S. Shalet (UK)
   
09:30 11:30  ISE General Council Meeting (Invitation Only)
Location: Teatrino
11:00 11:30  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
11:30 12:30  Debate 2: This house believes that calcium supplementation causes heart attacks
For: I. Reid (New Zealand); Against: C. Weaver (USA)
Location: Main Hall
Chair: Chair(s): J. Bollerslev (Norway)
11:30 13:15  ISE Travel Grant Reception (Invitation Only)
11:30 12:15  Meet the Expert 1 - Repeated
Location: Hall A
11:30MTE1Adrenal incidentaloma and subclinical Cushing's syndrome
P. Stewart (UK)
   
11:30 12:15  Meet the Expert 2 - Repeated
Location: Hall B
11:30MTE2Approach to the patient with Cushing's disease after pituitary surgery failure
M. Toth (Hungary)
   
11:30 12:15  Meet the Expert 3 - Repeated
Location: Hall C
11:30MTE3Osteoporosis in men
U. Gruntmanis (USA)
   
11:30 12:15  Meet the Expert 4 - Repeated
Location: Hall D
11:30MTE4Challenges of transsphenoidal pituitary surgery
P. Cappabianca (Italy)
   
11:30 12:15  Meet the Expert 5 - Repeated
Location: Hall E
MTE5Discussions of common but difficult thyroid cancer cases
L. Wartofsky (USA)
   
11:30 12:15  Meet the Expert 6 - Repeated
Location: Hall F
11:30MTE6Clinical management of adrenocortical carcinoma
M. Terzolo (Italy)
   
11:30 12:15  Meet the Expert 7 - Repeated
Location: Hall G
11:30MTE7Pregnancy and pituitary disorders
Z. Karaca (Turkey)
   
11:30 12:15  Meet the Expert 8 - Repeated
Location: Hall H
11:30MTE8Diagnosis and treatment of precocious puberty
L. Ghizzoni (Italy)
   
12:25 13:10  Meet the Expert 9 - Repeated
Location: Hall A
12:25MTE9Diagnosis and treatment of SIADH
C. Thompson (Ireland)
   
12:25 13:10  Meet the Expert 10 - Repeated
Location: Hall B
12:25MTE10Elastosonography in the evaluation of thyroid and parathyroid lesions
M. Erdogan (Turkey)
   
12:25 13:10  Meet the Expert 11 - Repeated
Location: Hall C
12:25MTE11Diagnosis and treatment considerations in autoimmune polyendocrine syndrome type 1
O. Kampe (Sweden)
   
12:25 13:10  Meet the Expert 12 - Repeated
Location: Hall D
12:25MTE12Goitre throughout the paediatric ages
M. Polak (France)
   
12:25 13:10  Meet the Expert 13 - Repeated
Location: Hall E
12:25MTE13Graves' ophthalmopathy
W. Wiersinga (The Netherlands)
   
12:25 13:10  Meet the Expert 14 - Repeated
Location: Hall F
12:25MTE14Hirsutism
K. Unluhizarci (Turkey)
   
12:25 13:10  Meet the Expert 15 - Repeated
Location: Hall G
12:25MTE15Pituitary tumours in adolescents and adults
M. Andersen (Denmark)
   
12:25 13:10  Meet the Expert 16 - Repeated
Location: Hall H
12:25MTE16Management of non-functioning pituitary adenomas
N. Karavitaki (UK)
   
12:30 13:15  Lunch, Posters & Exhibition
ESE President meets ESE New Members (invitation only)
Exhibition Hall & Poster Hall
13:15 14:45  Symposium 26: TSH Receptor
Location: Hall A
Chairs: Chair(s): R. Paschke (Germany) & E. Martino (Italy)
13:15S26.1Low-molecular weight antagonists of the TSH receptor
M. Gershengorn (USA)
   
13:45S26.2Epitope geography and intracellular pathways of TSH receptor antibodies
T. Davis (USA)
   
14:15S26.3Structure and function of TSH receptor
H. Biebermann (Germany)
   
13:15 14:45  Symposium 27: Are endogenous testosterone levels predictors of cardiovascular events?
Location: Hall B
Chairs: Chair(s): C. Wang (USA) & K. Channer (UK)
13:15S27.1Androgen action on the cardiovascular system
K. Channer (UK)
   
13:45S27.2Testosterone deficiency, cardiometabolic and mortality risks in men: the European Male Ageing Study (EMAS)
F. Wu (UK)
   
14:15S27.3Endogenous androgens, diabetes, and cardiovascular disease in women: The rancho bernado study
E. Barrett-Connor (USA)
   
13:15 14:45  Symposium 28: Osteoporosis treatment in 2012 and beyond
Location: Hall C
Chairs: Chair(s): G. Borretta (Italy) & J. Stepan (Czech Republic)
13:15S28.1Controversial issues with bisphosphonate treatment
S. Papapoulos (The Netherlands)
   
13:45S28.2Sclerostin - a key bone regulatory molecule
M. Robinson (USA)
   
14:15S28.3Other emerging therapies
P. Ebeling (Australia)
   
13:15 14:45  Symposium 29: Are we ready for novel therapies in obesity?
Location: Hall D
Chairs: Chair(s): F. Giorgino (Italy) & U. Pagotto (Italy)
13:15S29.1GI Hormone-based polypharmacy for the treatment of obesity
M. Tschoep (Germany)
   
13:45S29.2Growth hormone replacement and metabolic syndrome in GH deficient adults
D. Clemmons (USA)
   
14:15S29.3The ghrelin-GOAT system links dietary lipids with the endocrine control of energy balance
P. Pfluger (Germany)
   
13:15 14:45  Symposium 30: New developments in pituitary adenomas
Location: Hall E
Chairs: Chair(s): G. Raverot (France) & G. Lombardi (Italy)
13:15S30.1New developments in pituitary adenoma cytokines & other new genes in pituitary adenomas
E. Arzt (Argentina)
   
13:45S30.2'Dopastatin': an evolving story
T. Brue (France)
   
14:15S30.3The use of temozolomide in pituitary tumours
A. McCormack (Australia)
   
13:15 14:45  Symposium 31: Progress in treatment in primary aldosteronism
Location: Hall F
Chairs: Chair(s): J. Widimsky (Czech Republic) & P. Mulatero (Italy)
13:15S31.1Epidemiology and diagnosis of primary aldosteronism
P-F. Plouin (France)
   
13:45S31.2Surgery
M. Walz (Germany)
   
14:15S31.3Medical treatment
L. Sechi (Italy)
   
13:15 14:45  Symposium 32: Disorders of sex development (DSD)
Location: G
Chairs: Chair(s): P. Lee (USA) & P. Cohen-Kettenis (The Netherlands)
13:15S32.1Genetics of disorders of sex development
T. Ogata (Japan)
   
13:45S32.2Psychosocial and psychosexual outcome in DSD
P. Cohen-Kettenis (The Netherlands)
   
14:15S32.3Review of clinical guidelines
F. Ahmed (UK)
   
13:15 14:45  Symposium 33: Environment Induced Endocrine Disease
Location: Hall H
Chairs: Chair(s): M. Shupnik (USA) & J. Toppari (Finland)
13:15S33.1Pollution related acromegaly
S. Cannavo (Italy)
   
13:45S33.2Exposure to endocrine disrupting chemicals may interfere with reproductive development in humans and affect timing of puberty
K. Main (Denmark)
   
14:15S33.3Effect of iodine intake on thyroid disease in China
W. Teng (China)
   
14:45 15:15  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
15:15 16:45  Symposium 34: Effects of thyroid hormone derivatives
Location: Main Hall
Chairs: Chair(s): P. Laurberg (Denmark) & F. Monaco (Italy)
15:15S34.1Pathways of thyroid hormone metabolism
J. Koehrle (Germany)
   
15:45S34.2Thyroid hormone mimetic compounds
T. Scanlan (USA)
   
16:15S34.3Trials of thyroid hormone analogues
P. Ladenson (USA)
   
15:15 16:45  Symposium 35: Endocrinology and the Olympics: Will hormones help to win?
Location: Hall A
Chairs: Chair(s): E. Ghigo (Italy) & R. Ross (UK)
15:15S35.1Does the high performance athlete need hormone replacement?
L. Di Luigi (Italy)
   
15:45S35.2Can an endocrine patient participate in high performance sports?
R. Auchus (USA)
   
16:15S35.3Hormone abuse in sports: the knowns and unknowns
M. Thevis (Germany)
   
15:15 16:45  Symposium 36: Bone and metabolism
Location: Hall B
Chairs: Chair(s): J.Eisman (Australia) & J.J.Body (Belgium)
15:15S36.1Leptin and bone signalling
S. Takeda (Japan)
   
15:45S36.2Insulin bone axis
T. Clemens (USA)
   
16:15S36.3Functions and mode of action of osteocalcin
G. Karsenty (USA)
   
15:15 16:45  Symposium 37: Diabetes and cancer
Location: Hall C
Chairs: Chair(s): L. Bach (Austria) & A. Abdel Raheem (Egypt)
15:15S37.1Epidemiological evidence for a link between diabetes and cancer
A. Renehan (UK)
   
16:00S37.2The role of the insulin receptor in cancer
A. Belfiore (Italy)
   
15:15 16:45  Symposium 38: Craniopharyngioma: Hypothalamic complications
Location: Hall D
Chairs: Chair(s): J. Hamilton (Canada) & M. Puig-Domingo (Spain)
15:15S38.1Childhood craniopharyngioma
H. Müller (Germany)
   
15:45S38.2Hypothalamic disorders in craniopharyngioma; relevance to clinical practice
C. Thompson (Ireland)
   
16:15S38.3Management of hypothalamic obesity in patients with craniopharyngioma
G. Wittert (Australia)
   
15:15 16:45  Symposium 39: Adrenal insufficiency
Location: Hall E
Chairs: Chair(s): W. Arlt (UK) & C. Betterle (Italy)
15:15S39.1Pathomechanism underlying adrenoleucodystrophy
G. Raymond (USA)
   
15:45S39.2Molecular pathomechanisms of steroidogenetic adrenal disorders
F. Riepe (Germany)
   
16:15S39.3New developments in the immunology of Addison's disease
E. Husebye (Norway)
   
15:15 16:45  Symposium 40: New familial endocrine cancer syndromes: pathophysiology and counselling
Location: Hall F
Chairs: Chair(s): E. Lalli (France) & D. Malkin (Canada)
15:15S40.1DICER1 mutations characterize a novel syndrome with endocrine features
W. Foulkes (Canada)
   
15:45S40.2The paediatric patient with paraganglioma syndrome
M. Robledo (Spain)
   
16:15S40.3Li-Fraumeni syndrome: A paradigm of genetic testing to clinical surveillance for pediatric endocrine tumors
D. Malkin (Canada)
   
15:15 16:45  Symposium 41: The endocrinology of adipose tissue
Location: Hall G
Chair: Chair(s): M. Luconi (Italy)
15:15S41.1Physiological and neuronal determinants of brown adipose tissue-mediated thermogenesis in small mammals and humans
D. Richard (Canada)
   
15:45S41.2Obesity and insulin resistance: the cross-talk macrophage-adipocyte view
J. Fernandez-Real (Spain)
   
16:15S41.3The fat cell: dynamics, genomics and adipokines
P. Arner (Sweden)
   
15:15 16:45  Symposium 42: Novel insights into regulation of puberty
Location: Hall H
Chairs: Chair(s): E. Malecka-Tendera (Poland) & M. Cappa (Italy)
15:15S42.1Central networks controlling the timing of puberty
A. Lomniczi (USA)
   
15:45S42.2Re-wiring the hypothalamus with new peptides to control puberty
V. Navarro (USA)
   
16:15S42.3Novel insights into regulation of puberty: lessons from human genetics
B. Mendonca (Brazil)
   
16:35 17:10  JOE / JME Prize Presentation
Location: Main Hall
Chair: Chair(s): A. Clark (UK)
17:10 17:55  Fondation IPSEN 2012 Endocrine Regulation Prize
Location: Main Hall
17:10IFPL1Wylie Vale Endocrine Prize Lecture at the 2012 ICE/ECE Congress
P. Sassone Corsi (USA)
   
17:55 19:30  Poster Reception
Attended poster session, refreshments available
Poster Hall
18:30 20:00  IPSEN Satellite Symposia - Acromegaly: patient-focused disease control and long-term outcomes
Location: Hall B
18:30Welcome
E. Ghigo (Italy)
   
18:35Biochemical determinants of long-term outcomes
S. Lamberts (The Netherlands)
   
18:55Clinical determinants of long-term outcomes
A. Giustina (Italy)
   
19:15Therapeutic determinants of long-term outcomes
M. Gadelha (Brazil)
   
19:35Economic burden of long-term acromegaly management
S. Melmed (USA)
   
19:55Summary and close
S. Melmed (USA)
   
18:30 20:00  NOVARTIS Satellite Symposia - Taking the next step: improving outcomes in patients with pituitary tumors
Location: Main Hall
Chair: A-M. Colao (Italy)
18:30Welcome and Introduction
A-M. Colao (Italy)
   
18:35Advancing the partnership: A multidisciplinary approach to treating Cushing's disease
P. Cappabianca (Italy)
   
18:50Walking in their shoes: Case studies of Cushing's disease
I. Shimon (Israel)
   
19:05Toeing the line: Criteria for and achievement of control in acromegaly
J. Wass (UK)
   
19:20Striding towards the future: Somatostatin analogues for acromegaly
A-M. Colao (Italy)
   
19:40Panel discussion
A-M. Colao (Italy), P. Cappabiance (Italy), I. Shimon (Israel), J. Wass (UK)
   
19:55Concluding remarks
A-M. Colao (Italy)
   
18:30 20:00  PROSTRAKAN Satellite Symposia - Testosterone replacement therapy - benefits & risks?
Location: Hall F
Chair: M. Maggi
18:30Welcome, Opening Remarks & Introduction
M. Maggi (Florence, Italy)
   
18:35Testosterone - emerging data for the management of hypogonadel men with Type 2 diabetes
H. Jones (Barnsley, UK)
   
19:00Testosterone - emerging data for the management of hypogonadel men with heart disease
K. Channer (Sheffield, UK)
   
19:25Testosterone replacement therapy and prostate diseases
M. Maggi (Florence, Italy)
   
19:50Q&A and Chairman's Concluding Comments
   
20:30 21:15  ICE/ECE 2012 Congress Concert
Tickets should be purchased during registration
Basilica di San Lorenzo
8 May 2012
07:00 20:00  Registration
07:00 08:30  Industry Sponsored Satellite Symposia
08:30 09:15  Plenary Lecture 4
Location: Main Hall
Chair: Chair(s): P. Bouchard (France)
08:30PL4Cushing Syndrome: Minnie G. and the Next 100 Years
A lecture given by the Endocrine Society President-Elect
W. Young (USA)
   
09:30 11:00  Oral Communication Session 10 - Pituitary Clinical 2
Location: Hall A
Chairs: Chair(s): J. Christiansen (Denmark) & A. Peri (Italy)
09:30OC10.1Predictors of morbidity and mortality in acromegaly: an Italian survey on behalf of the Italian Study Group of Acromegaly
M. Arosio (Italy)
   
09:45OC10.2Food intake regulating hormones in adult craniopharyngioma patients
J. Roemmler (Germany)
   
10:00OC10.3Pathophysiology of renal calcium handling in acromegaly revisited
P. Kamenicky (France)
   
10:15OC10.4Higher glucocorticoid supplementation doses are associated with increased overall mortality in patients with non-functioning pituitary adenoma
T. Zueger (Switzerland)
   
10:30OC10.5Once-Weekly, CTP-modified hGH (MOD-4023) is Effective in Growth Hormone Deficient Adults: A Phase II, Dose and Frequency Finding Study
V. Popovic (Serbia)
   
10:45OC10.6Second neoplasms in childhood cancer survivors with growth hormone deficiency treated or not treated with GH
F. Felicetti (Italy)
   
09:30 11:00  Oral Communication Session 11 - Thyroid Clinical 2
Location: Hall B
Chairs: Chair(s): L. Hegedus (Denmark) & C. Chang (Taiwan)
09:30OC11.1Growth retardation and severe constipation due to the first human, dominant negative thyroid hormone receptor alpha mutation
N. Schoenmakers (UK)
   
09:45OC11.2Subclinical thyroid disease and risk of new-onset atrial fibrillation
C. Selmer (Denmark)
   
10:00OC11.3Is overt hypothyroidism associated with increased mortality? A nationwide register-based study of disease discordant Danish twins
M. Thvilum (Denmark)
   
10:15OC11.4The frequency of TSH receptor mutation and clinical characteristics among 84 patients with hyperthyroidism with diffuse goiter and negative TBII
E. Nishihara (Japan)
   
10:30OC11.5Thyroid hormones and male sexual function
G. Corona (Italy)
   
10:45OC11.6Is age a risk factor for hypothyroidism in pregnancy? An analysis of 5223 pregnant women
E. Potlukova (Czech Republic)
   
09:30 11:00  Oral Communication Session 12 - Obesity Clinical
Location: Hall C
Chairs: Chair(s): J. Tomlinson (UK) & M. Bielhouby (Germany)
09:30OC12.1Circulating endocannabinoids are associated to cardiometabolic alterations independently from adiposity
F. Fanelli (Italy)
   
09:45OC12.2Lipid-induced insulin resistance is associated with a reduction of IGF-I bioactivity independent of changes in IGFBP-1 and -2 in humans
A. Arafat (Germany)
   
10:00OC12.3Transient increase of beta-cell first phase secretion after smoking cessation - a possible contributor to carbohydrate craving and body weight gain?
M. Stadler (Austria)
   
10:15OC12.4Genetic susceptibility, birth weight and obesity risk in young Chinese
J. Hong (China)
   
10:30OC12.5Brown adipose tissue activation is inversely related with central obesity and metabolic parameters in adult human
W. Wang (China)
   
10:45OC12.6Eating speed and the risk of type 2 diabetes mellitus: a case-control study
L. Radzeviciene (Lithuania)
   
09:30 11:00  Oral Communication Session 13 - Adrenal Basic
Location: Hall D
Chairs: Chair(s): M-C. Zennaro (France) & S. Hahner (Germany)
09:30OC13.1Targeting multiple signalling pathways showed high anti-tumour potential in two mouse phaeochromocytoma cell lines
S. Nölting (UK)
   
09:45OC13.2VSNL1 is upregulated in aldosterone producing adenomas with KCNJ5 mutations and protects from calcium-induced apoptosis
S. Monticone (Italy)
   
10:00OC13.3Cortisol secretion is dependent on intraadrenal production of ACTH in macronodular bilateral adrenal hyperplasia causing Cushing's syndrome
E. Louiset (France)
   
10:15OC13.4A genome-wide methylation study of adrenocortical tumors shows specific alterations linked to gene expression, revealing new aspects of the molecular classification of adrenal carcinomas
G. Assié (France)
   
10:30OC13.5KCNJ5 mutations in Japanese patients with aldosterone-producing adenomas
M. Yamada (Japan)
   
10:45OC13.6GATA-4 overexpression induces adrenocortical tumorigenesis and ectopic expression of luteinizing hormone receptor in C57Bl/6J mice
M. Chrusciel (Finland)
   
09:30 11:00  Oral Communication Session 14 - Male Reproduction
Location: Hall E
Chairs: Chair(s): R. Swerdloff (USA) & C. Krausz
09:30OC14.1X chromosome-linked copy number variations in male infertility
C. Krausz (Italy)
   
09:45OC14.2Deficient expression of genes involved in the endogenous defense system against transposons in cryptorchid boys with impaired mini-puberty
F. Hadziselimovic (Switzerland)
   
10:00OC14.3Comparison of serum testosterone and estradiol levels in 3174 European men as measured by a platform immunoassay and mass spectrometry; relevance for the diagnostics in aging men
I. Huhtaniemi (UK)
   
10:15OC14.4The prevalence of hypogonadism in men on methadone maintenance.
A. McGowan (Ireland)
   
10:30OC14.5The Muenster EXAKT project: X-inactivation in Klinefelter patients
S. Werler (Germany)
   
10:45OC14.6Erectile dysfunction after liver transplantation
O. Levalle (Argentina)
   
09:30 11:00  Oral Communication Session 15 - Thyroid Basic
Location: Hall F
Chairs: Chair(s): L. Fugazzola (Italy) & S Gullu (Turkey)
09:30OC15.1PATZ1 is a new candidate tumour-suppressor gene in thyroid cancer
M. Fedele (Italy)
   
09:45OC15.2Ligand bound-thyroid hormone receptor contributes to reprogramming of pancreatic exocrine cells to insulin-producing cells via induction of Ngn3 and MafA
F. Furuya (Japan)
   
10:00OC15.3Radioiodine therapy of non-thyroidal cancer following systemic sodium iodide symporter (NIS) gene transfer using Transferrin-receptor (Tfr) targeted non-viral gene delivery vectors
M. J Willhauck (Germany)
   
10:15OC15.4The DNA methylation as a predisposition factor in the pathogenesis of congenital hypothyroidism in premature infants
F. Marelli (Italy)
   
10:30OC15.5Lymphatic endothelial markers podoplanin and PROX1 in differentiated thyroid tumours
J. Janik (Poland)
   
10:45OC15.6Thyroglobulin induces thyroid cell growth through suppression of miR-16 and miR-195
T. Akama (Japan)
   
09:30 11:00  Oral Communication Session 16 - Female Reproduction Clinical
Location: Hall G
Chairs: Chair(s): T. Sir-Petermann (Chile) & A. Gambineri (Italy)
09:30OC16.1The association between birth weight and PCOS in adult life. A register-based study on 523,757 Danish women born 1973-1991
H. Mumm (Denmark)
   
09:45OC16.2The first missense mutation of BMP15 mature domain identified in a Chinese family with primary ovarian insufficiency causes defective production of the bioactive protein
R. Rossetti (Italy)
   
10:00OC16.3Anti-muellerian hormone as a predictor of ovarian response to weight loss in overweight women with polycystic ovary syndrome
P. Popova (Russia)
   
10:15OC16.4Epidemiological survey on the prevalence of hyperandrogenic states in adolescent and young women
A. Gambineri (Italy)
   
10:30OC16.5Urinary glucocorticoid metabolite excretion is associated with insulin resistance independent of body mass index (BMI) in patients with polycystic ovary syndrome
M. O'Reilly (UK)
   
10:45OC16.6Kisspeptin-10 stimulation of gonadotropin secretion in women is modulated by sex steroid feedback
J. George (UK)
   
09:30 11:00  Oral Communication 17 - Diabetes Basic
Location: Hall H
Chairs: Chair(s): A. Belfiore (Italy) & S. Assaad (Egypt)
09:30OC17.1Pdk1/Foxo1 pathway regulates macrophage migration, polarization, and insulin sensitivity
Y. Kawano (Japan)
   
09:45OC17.2Placental restriction co-ordinately alters hepatic expression of microRNAs and targets related to non alcoholic fatty liver disease, in adult male sheep
J. Owens (Australia)
   
10:00OC17.3Caerulin Precursor Fragment (CPF-AM1): A novel insulinotropic peptide from the skin secretion of the clawed frog, Xenopus amieti
O. Ojo (UK)
   
10:15OC17.4Syntaxin-3 regulates recruitment and exocytosis of newcomer insulin granules and granule-granule fusion during biphasic glucose-stimulated insulin secretion in pancreatic β-cells
H. Gaisano (Canada)
   
10:30OC17.5Glucocorticoid receptor alpha expression is downregulated in gluteal subcutaneous adipose tissue of black south african women and associates with increased metabolic risk
J. Goedecke (South Africa)
   
10:45OC17.6Meta-analysis of differentially expressed microRNAs in type 1, type 2 and gestational diabetes mellitus
E. Donadi (Brazil)
   
09:30 11:00  Oral Communication 18 - Paediatric Endocrinology
Location: Teatrino
Chairs: Chair(s): R. Voutilainen (Finland) & C. Deal (Canada)
09:30OC18.1Mutations in the NR5A1 gene in patients with 46,XY disorders of sex development (DSD): High frequency of familial multi-generational occurrence
M. Costanzo (Argentina)
   
09:45OC18.2Clinical profile, gender choice and long term follow up of subjects with 5 alpha-steroid reductase 2 deficiency
A. Ammini (India)
   
10:00OC18.3Effects of vitamin D insufficiency and its correction on insulin sensitivity and serum osteocalcin concentration in obese children
P. Nantarakchaikul (Thailand)
   
10:15OC18.4Mortality in GH-treated (Tx) patients enrolled in the global Genetics and Neuroendocrinology of Short Stature International Study (GeNeSIS)
C. Child (UK)
   
10:30OC18.5Earlier reactivation of the hypothalamo-pituitary-gonadal axis and advancement of puberty in boys under labour stress
A. Naseem (Pakistan)
   
10:45OC18.6Functional characterization of a new mutation in the NKX2.1 in patients with thyroid-lung-brain syndrome
I. Nettore (Italy)
   
09:30 11:00  Oral Communicatin Session 19 - Cardiovascular Endocrinology
Location: Basilica
Chairs: Chair(s): M. Alevizaki (Greece) & H. Romjin (The Netherlands)
09:30OC19.1Both EPA/AA ratio and absolute AA levels constitute an independent risk factor for coronary atherosclerosis in type 2 diabetic patients
T. Nakamua (Japan)
   
09:45OC19.2Increased arterial stiffness is independently associated with cerebral infarctions and white matter lesions in patients with type 2 diabetes despite good blood pressure and lipid control
E. Laugesen (Denmark)
   
10:00OC19.3Copeptin and adrenomedullin in a large cohort of patients with coronary heart disease and newly diagnosed glucose intolerance (“Silent diabetes study”)
T. Lohmann (Germany)
   
10:15OC19.4Oxytocin is cardioprotective hormone
J. Gutkowska (Canada)
   
10:30OC19.5Circulating adrenomedulin levels are associated with atrial natriuretic peptide and brain natriuretic peptide levels in heart failure patients
P. Holmager (Denmark)
   
10:45OC19.6Endothelial progenitor cells in acromegaly are reduced and responsive to treatmet with somatostatin analogues
P. Maffei (Italy)
   
09:30 11:00  Endocrine Nurses' Session: Cushing's and Prolactinoma - diagnosis and management
Polveriera
Chairs: Chair(s): M. Valota, Italy & P. Burman, Sweden
09:30EN2.1Diagnosis and management of cushing's syndrome
R. Feelders (The Netherlands)
   
10:00EN2.2The role of the endocrine nurse in the diagnosis and management of the patient with cushing's syndrome
W. Geilvoet (The Netherlands)
   
10:15EN2.3Diagnosis and management of prolactinoma
M. Andersen (Denmark)
   
10:45EN2.4The role of the endocrine nurse in the diagnosis and management of the patient with prolactinoma
A. Marland (UK)
   
11:00 11:30  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
11:30 12:30  Debate 3: This house believes that PCOS needs a new name
For: H. Teede (Australia); Against: D. Dewailly (France)
Location: Main Hall
Chair: Chair(s): A. Dunaif (USA)
11:30 12:15  Meet the Expert 17
Location: Hall A
11:30MTE17Multiple endocrine neoplasia type II
F. Raue (Germany)
   
11:30 12:15  Meet the Expert 18
Location: Hall B
11:30MTE18Normocalcemic primary hyperparathyroidism
C. Marcocci (Italy)
   
11:30 12:15  Meet the Expert 19
Location: Hall C
11:30MTE19Maturity onset diabetes of the young
A. Hattersley (UK)
   
11:30 12:15  Meet the Expert 20
Location: Hall D
11:30MTE20The diagnosis and treatment of secondary osteoporosis in children
L. Ward (USA)
   
11:30 12:15  Meet the Expert 21
Location: Hall E
11:30MTE21Autoimmune hyperthyroidism: Initiation and duration of thionamide therapy
P. Laurberg (Denmark)
   
11:30 12:15  Meet the Expert 22
Location:Hall F
11:30MTE22Clinical management in transgender sex hormone treatment
G. T'Sjoen (Belgium)
   
11:30 12:15  Meet the Expert 23
Location: Hall G
11:30MTE23Subclinical hypothyroidism
B. Biondi (Italy)
   
11:30 12:15  Meet the Expert 24
Location: Hall H
11:30MTE24Approach to the management of the infertile couple
A. Lenzi (Italy)
   
12:25 13:10  Meet the Expert 25
Location: Hall A
12:25MTE25Pituitary incidentalomas
S. Tsagarakis (Greece)
   
12:25 13:10  Meet the Expert 26
Location: Hall B
12:25MTE26PCOS
E. Diamanti-Kandarakis (Greece)
   
12:25 13:10  Meet the Expert 27
Location: Hall C
12:25MTE27Differential diagnosis of Cushing's syndrome
J. Salvador (Spain)
   
12:25 13:10  Meet the Expert 28
Location: Hall D
12:25MTE28Hypoglycaemia and diabetes management
W. Sheu (Taiwan)
   
12:25 13:10  Meet the Expert 29
Location: Hall E
12:25MTE29Management of bone loss induced by cancer treatment in early breast and prostate cancer
J. Body (Belgium)
   
12:25 13:10  Meet the Expert 30
Location: Hall F
12:25MTE30Treatment of vitamin D deficiency
N. Tandon (India)
   
12:25 13:10  Meet the Expert 31
Location: Hall G
12:25MTE31Cryptorchidism
J. Toppari (Finland)
   
12:25 13:10  Meet the Expert 32
Location: Hall H
12:25MTE32Management of GEP-NET tumours
K. Oberg (Sweden)
   
12:30 13:15  Lunch, Posters & Exhibition
Exhibition Hall & Poster Hall
12:30 13:15  ESE Annual General Meeting
ESE Members Only - Lunch Provided
Teatrino
13:15 14:45  Symposium 43: Graves' orbitopathy (GO)
Location: Hall A
Chairs: Chair(s): A. Karlsson (Sweden) & W. Wiersinga (The Netherlands)
13:15S43.1Immunopathogenesis of Graves' orbitopathy
R. Bahn (USA)
   
13:45S43.2How to restore euthyroidism in the presence of Graves’ orbitopathy? Is there a best way?
L. Hegedus (Denmark)
   
14:15S43.3Progress in immunosuppressive treatment of GO (selenium, steroid dosage, rituximab)
L. Bartalena (Italy)
   
13:15 14:45  Symposium 44: Genome wide studies in reproduction
Location: Hall B
Chairs: Chair(s): M. Urbanek (USA) & J. Laven (The Netherlands)
13:15S44.1Genome-wide association study of endometriosis identifies a locus at 7p15.2 with pleiotropic effects
K. Zondervan (UK)
   
13:45S44.2Genetic studies on polycystic ovary syndrome
Z-J. Chen (China)
   
14:15S44.3Genetics of (in)fertility
J. Laven (Netherlands)
   
13:15 14:45  Symposium 45: Bone quality and bone strength
Location: Hall C
Chairs: Chair(s): E. Seeman (Australia) & M. Brandi (Italy)
13:15S45.1Bone quality and micro architecture
R. Rizzoli (Switzerland)
   
13:45S45.2Finite element analysis in osteology
P. Zysset (Austria)
   
14:15S45.3Non-invasive assessment of bone mass by various modalities
R. Prince (Australia)
   
13:15 14:45  Symposium 46: Chronic inflammation and insulin resistance
Location: Hall D
Chairs: Chair(s): E. Bonora (Italy) & P. Scherer (USA)
13:15S46.1AIMing at Metabolic Syndrome: Towards development of novel therapies for modern metabolic diseases via macrophage-derived AIM
T. Miyazaki (Japan)
   
13:45S46.2Macrophage regulation of adipocyte biology
P. Scherer (USA)
   
14:15S46.3The inflammatory-adipokine hypothesis and stem cell abnormalities
R. Vettor (Italy)
   
13:15 14:45  Symposium 47: Cushing's syndrome
Location: Main Hall
Chairs: Chair(s): N. Shah (India) & L. Nieman (USA)
13:15S47.1Long term sequelae of 'cured' Cushing's syndrome
J. Newell-Price (UK)
   
13:45S47.2Established and new medical treatment options for Cushing's disease
A. Tabarin (France)
   
14:15S47.3Learnings from ERCUSYN: The first 500 patients
E. Valassi (Spain)
   
13:15 14:45  Symposium 48: Pathogenesis of primary aldosteronism
Location: Hall E
Chairs: Chair(s): F. Mantero (Italy) & W. Rainey (USA)
13:15S48.1Genomic profile in primary aldosteronism
P. Hellman (Sweden)
   
13:45S48.2Integrating genetics and genomics in primary aldosteronism
M.C. Zennaro (France)
   
14:15S48.3Potassium channels in primary aldosteronism
R. Warth (Germany)
   
13:15 14:45  Symposium 49: Genetic breakthroughs in reproductive pathology and physiology
Location: Hall F
Chairs: Chair(s): J. Young (France) & P. Beck-Peccoz (Italy)
13:15S49.1New mechanisms of hypothalamic amenorrhea
N. Pitteloud (Switzerland)
   
14:00S49.3RANK ligand mediates hormone induced mammary epithelial proliferation and carcinogenesis
E. Gonzalez-Suarez (Spain)
   
13:15 14:45  Symposium 50: Circadian regulation of metabolism
Location: Hall G
Chairs: Chair(s): J. Klein (Germany) & E. van Cauter (USA)
13:15S50.1Basic mechanisms of circadian regulation in the brain
H. Oster (Germany)
   
13:45S50.2Metabolic dysfunction: impact of circadian and sleep regulation
E. van Cauter (USA)
   
14:15S50.3Circadian rhythms in adipose tissue
J. Gimble (USA)
   
13:15 14:45  Symposium 51: Recent management of pheochromocytoma / paraganglioma syndrome
Location: Hall H
Chairs: Chair(s): M. Mannelli (Italy) & Z-P. Zeng (China)
13:15S51.1Recent progress in biochemical testing for pheochromocytoma
S. Petersenn (Germany)
   
13:45S51.2Prevalence of SDH gene mutations in pheochromocytoma
G. Opocher (Italy)
   
14:15S51.3Treatment of malignant pheochromocytoma
A. Tanabe (Japan)
   
14:45 15:15  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
15:15 16:45  Symposium 52: Thyroid & pregnancy
Location: Main Hall
Chairs: Chair(s): K. Poppe (Belgium) & A. Pinchera (Italy)
15:15S52.1Outcome of the Controlled Antenatal Thyroid Screening Study (CATS) study
J. Lazarus (UK)
   
15:45S52.2The case for thyroid screen in pregnancy
R. Negro (Italy)
   
16:15S52.3Challenges with diagnosis and treatment of hyperthyroidism in pregnancy
F. Azizi (Iran)
   
15:15 16:45  Symposium 53: Genetic polymorphism in reproduction
Location: Hall A
Chairs: Chair(s): C. Krausz (Italy) & A. Latronico (Brazil)
15:15S53.1Genetic variation of the androgen receptor: from gene regulation to prostate cancer
M. Zitzmann (Germany)
   
15:45S53.2Gene polymorphisms and male infertility
S. Repping (The Netherlands)
   
16:15S53.3Genetic complexity of FSH reception function
M. Simoni (Italy)
   
15:15 16:45  Symposium 54: Vitamin D
Location: Hall B
Chairs: Chair(s): P. Lips (The Netherlands) & R. Bouillon (Belgium)
15:15S54.1Vitamin D is a multifunctional hormone
R. Bouillon (Belgium)
   
15:45S54.2Vitamin D and primary hyperparathyroidism
L. Mosekilde (Denmark)
   
16:15S54.3Vitamin D and falls
H. Bischoff-Ferrari (USA)
   
15:15 16:45  Symposium 55: The fatty liver as an endocrine disease
Location: Hall C
Chairs: Chair(s): J. Tomlinson (UK) & M. Tschoep (Germany)
15:15S55.1Pathogenesis of fatty liver disease
C. Postic (France)
   
15:45S55.2Insulin sensitizer treatment of fatty liver disease
K. Cusi (USA)
   
16:15S55.3Fatty liver disease in childhood
V. Nobili (Italy)
   
15:15 16:45  Symposium 56: Pituitary development transcription factors: stem cells and beyond
Location: Hall D
Chairs: Chair(s): M. Dattani (UK) & C. Bousquet (France)
15:15S56.1The GPS niche of stem cells in the pituitary
C.V. Alvarez (Spain)
   
15:45S56.2LHX3: An insightful model of pituitary hormone deficiency
S. Rhodes (USA)
   
16:15S56.3Transcriptional and epigenetic mechanisms for cell fate choice in pituitary
J. Drouin (Canada)
   
15:15 16:45  Symposium 57: What's new in congenital adrenal hyperplasia (CAH)?
Location: Hall E
Chairs: Chair(s): L. Ghizzoni (Italy) & N. Reisch (Germany)
15:15S57.1Congenital adrenal hyperplasia: Counselling from birth to the next generation
N. Krone (UK)
   
15:45S57.2CAH and adulthood
R. Ross (UK)
   
16:15S57.3Optimal replacement therapy
N. Reisch (Germany)
   
15:15 16:00  Symposium 58: Best Clinical Practice
Location: Hall F
Chairs: P. Stewart (UK) & A. Peri (Italy)
15:15S58.1Towards European guidelines for treatment of hyponatraemia
B. Allolio (Germany)
   
15:15 16:45  Symposium 59: Obesity and thyroid function
Location: Hall G
Chairs: Chair(s): C. Schalin-Jaentti (Finland) & E. Papini (Italy)
15:15S59.1Obesity and thyroid function
T. Reinehr (Germany)
   
15:45S59.2Thyroid regulation of energy balance: the role of the hypothalamus
A. Vidal-Puig (UK)
   
16:15S59.3Type 2 deiodinase in muscle during health and disease
A. Boelen (The Netherlands)
   
15:15 16:45  Symposium 60: Performance enhancing hormones in sports
Location: Hall H
Chairs: Chair(s): M. Bidlingmaier (Germany) & J. Jorgensen (Denmark)
15:15S60.1The spectrum of hormones in sports doping
F. Lanfranco (Italy)
   
15:45S60.2Growth hormone and testosterone - do they work?
V. Birzniece (Australia)
   
16:15S60.3Erythropoietin and its derivatives
M. Saugy (Switzerland)
   
17:00 17:15  ESE Young Investigator Awards & Poster Prizes
Generously supported by Novartis
Location: Main Hall
17:15 18:00  Plenary Lecture 5
Location: Main Hall
Chair: Chair(s): H. Kronenberg (USA)
17:15PL5Why your bones break - from childhood to old age
E. Seeman (Australia)
   
18:00 19:45  Poster Reception
Attended poster session, refreshments available
18:30 20:00  ELI LILLY Satellite Symposia - Therapeutic advances in Type 2 Diabets: achieving long-term glycaemic control, patient by patient
Location: Hall A
18:30Pre-activity assessment
   
18:35iPod touch multimedia poster session
Poster 1 - Consensus and controversy in today's treatment landscape; Poster 2 - Emerging evidence and implications for treatment
S. Del Prato (Italy)
   
18:55Live Case Presentations: Applying therapeutic advances to clinical practice
S. Del Prato & I. Raz (Italy & Israel)
   
19:35Live Question & Answer Session
   
19:45iPod Touch Case-Based Video Presentation
F. Giorgino (Italy)
   
19:55Post-activity Assessment
   
20:00Programme Adjournment
   
18:30 20:00  Developing Endocrine Nursing across Europe and Internationally
Location: Polveriera
Chairs: Chair(s): M. Keil (USA) & P. Yeoh (UK)
18:30EN3.1Developing a nurse-led service in endocrinology
C. Follin (Sweden)
   
18:50EN3.2The role of nurse prescribing in the care of endocrine patients
S. Shalet (UK)
   
19:10EN3.3Developing an international endocrine nurse network - open discussion
Facilitators: M. Keil, USA & P.Yeoh, UK
   
19:20Announcement of Poster Prize, Posters display, networking and buffet meal
   
20:30 23:00  ESE President's Dinner (Invitation Only)
9 May 2012
07:30 14:00  Registration
08:00 08:45  Plenary Lecture 6
Location: Main Hall
Chair: Chair(s): C. Deal (Canada)
08:00PL6Maternal nutrition, metabolism and fetal programming
C.S. Yajnik (India)
   
09:00 10:30  Symposium 61: New insights in thyroid cancer diagnosis
Location: Main Hall
Chairs: Chair(s): D. Fuehrer (Germany) & A. Lewinski (Poland)
09:00S61.1BRAF(T1799A) can be detected in the blood of papillary thyroid carcinoma patients and correlates with disease status
M. Zatelli (Italy)
   
09:30S61.2Peripheral thyrotropin receptor mRNA as a novel marker for differentiated thyroid cancer diagnosis and surveillance
M. Milas (USA)
   
10:00S61.3Does circulating thyroglobullin mRNA and protein levels predict early midterm thyroid cancer recurrence?
A. Pontecorvi (Italy)
   
09:00 10:30  Symposium 62: Early Development and Treatment of PCOS
Location: Hall A
Chairs: Chair(s): E. Diamanti-Kandarakis (Greece) & L. Ibanez (Spain)
09:00S62.2Early development and pubertal prevention of polycystic ovary syndrome (PCOS)
F. de Zegher (Belgium)
   
09:30S62.1Early hormonal abnormalities in children born to women with PCOS
T. Sir-Petermann (Chile)
   
10:00S62.3Hyperandrogenism in obese girls - what is the significance?
C. McCartney (USA)
   
09:00 10:30  Symposium 63: Emerging ideas about phosphate metabolism
Location: Hall B
Chairs: Chair(s): O. Ljungren (Sweden) & T. Sugimoto (Japan)
09:00S63.1Genetics of phosphate metabolism
M. Econs (USA)
   
09:30S63.2FGF23: and tumour induced oestomalacia
S. Fukumoto (Japan)
   
10:00S63.3FGF23 in chronic renal failure
J. Silver (Israel)
   
09:00 10:30  Symposium 64: Endoplasmic reticulum stress, obesity and metabolic homeostasis
Location: Hall C
Chairs: Chair(s): J. Romijn (The Netherlands) & TBC
09:00S64.1Gut microbiota determine insulin sensitivity
M. Nieuwdorp (The Netherlands)
   
09:45S64.2Endoplasmic reticulum stress plays a central role in development of leptin resistance
C. Yi (Munich)
   
10:00S64.3P62, an autophagy hero or culprit?
H. Stenmark (Norway)
   
09:00 10:30  Symposium 65: Somatostatin receptors in pituitary
Location: Hall D
Chairs: Chair(s): J. Castano (Spain) & M. Gadelha (Brazil)
09:00S65.1Imaging somatostatin activity in live pituitary
S. Schulz (Germany)
   
09:30S65.2Is somatostatin receptor expression in adenomas related to pharmacological response?
S. Fougner (Norway)
   
10:00S65.3Somatostatin receptors and filamin: a developing story
C. Bousquet (France)
   
09:00 10:30  Symposium 66: HPA axis, stress metabolism and adaptation
Location: Hall E
Chairs: Chair(s): D. Ray (UK) & M. Fleseriu (USA)
09:00S66.1Neuroendocrine and (epi)genetic impact on HPA function
R. de Kloet (The Netherlands)
   
09:30S66.2HPA programming through perinatal epigenetic modifications
M. Meaney (Canada)
   
10:00S66.3Modulation of cortisol action
D. Ray (UK)
   
09:00 10:30  Symposium 67: Central regulation of energy homeostasis
Location: Hall F
Chairs: Chair(s): C. Strasburger (Germany) & A-M. Colao (Italy)
09:00S67.1CNS control of energy and glucose metabolism
C. Koenner (Germany)
   
09:30S67.2Gut hormones: history, physiology and therapeutic opportunities
K. Chandarana (UK)
   
10:00S67.3Novel pharmacological approaches to treatment of diabetes and obesity
M. Tschoep (USA)
   
09:00 10:30  Symposium 68: European Network for the Study of Adrenal Tumours (ENSAT)
Location: Hall G
Chairs: Chair(s): F. Beuschlein (Germany) & M. Mannelli (Italy)
09:00S68.1Genetics for Pheochromocytoma and paraganglioma in 2012
M. Robledo (Spain)
   
09:30S68.2Diagnostic, prognostic and predictive factors in adrenocortical cancer
M. Papotti (Italy)
   
10:00S68.3Update on hormonal markers as diagnostic and prognostic tools for adrenal lesions
W. Arlt (UK)
   
09:00 10:30  Symposium 69: Current progress in the management of thyroid cancer
Location: Hall H
Chairs: Chair(s): G. Brabant (Germany) & M Sahin (Turkey)
09:00S69.1TSH suppression in differentiated thyroid cancer: How low should we go?
D. Cooper (USA)
   
09:30S69.2rhTSH stimulated remnant ablation
M. Schlumberger (France)
   
10:00S69.3Tyrosine kinase inhibitions in the management of progressing thyroid cancer
S. Sherman (USA)
   
09:00 10:30  Symposium 70: Young Active Researchers Symposium (YARE)
Location: Polveriera
Chairs: Chair(s): C. Quarta (Italy) & M. Bielohuby (Germany)
09:00S70.1New mechanisms underlying the role of the mTORC1 pathway in the hypothalamic control of energy balance
D. Cota (France)
   
09:25S70.2Control of brown adipose tissue thermogenisis by GLP-1 receptor signalling in the brain
D. Perez-Tilve (USA)
   
09:50S70.3DNA methylation of the body weight-regulating proopiomelanocortin (POMC) gene: Functional and ontogenetic aspects
M. Mischke (Germany)
   
10:05S70.4Mineralocorticoid receptor (MR) antagonism counters metabolic dysfunctions induced by high fat diet in mice
F. Cinti (Italy )
   
10:20S70.5A four-week fat overfeeding study in constitutional thin women: a human model of weight gain resistance
B. Galusca (France)
   
10:45 11:30  Plenary Lecture 7
Location: Main Hall
Chair: Chair(s): J. Tomlinson (UK)
10:45PL7Diabetes as a gut disease
M. Nauck (Germany)
   
11:30 11:45  Coffee, Posters & Exhibition
Exhibition Hall & Poster Hall
11:45 12:45  Debate 4: This house believes that we do more harm than good in the treatment of thyroid low risk carcinoma
For: I. Hay (USA); Against: H. Dralle (Germany)
Location: Main Hall
Chair: Chair(s): M. Alevizaki (Greece)
11:45 12:30  Meet the Expert 17 - Repeated
Location: Hall A
11:45MTE17Multiple endocrine neoplasia type II
F. Raue (Germany)
   
11:45 12:30  Meet the Expert 18 - Repeated
Location: Hall B
11:45MTE18Normocalcemic primary hyperparathyroidism
C. Marcocci (Italy)
   
11:45 12:30  Meet the Expert 19 - Repeated
Location: Hall C
11:45MTE19Maturity onset diabetes of the young
A. Hattersley (UK)
   
11:45 12:30  Meet the Expert 20 - Repeated
Location: Hall D
11:45MTE20The diagnosis and treatment of secondary osteoporosis in children
L. Ward (USA)
   
11:45 12:30  Meet the Expert 21 - Repeated
Location: Hall E
11:45MTE21Autoimmune hyperthyroidism - initiation and duration of thionamide therapy
P. Laurberg (Denmark)
   
11:45 12:30  Meet the Expert 22 - Repeated
Location: Hall F
11:45MTE22Clinical management in transgender sex hormone treatment
G. T'Sjoen (Belgium)
   
11:45 12:30  Meet the Expert 23 - Repeated
Location: Hall G
11:45MTE23Subclinical hypothyroidism
B. Biondi (Italy)
   
11:45 12:30  Meet the Expert 24 - Repeated
Location: Hall H
11:45MTE24Approach to the management of the infertile couple
A. Lenzi (Italy)
   
12:45 13:30  Meet the Expert 25 - Repeated
Location: Hall A
12:45MTE25Pituitary incidentalomas
S. Tsagarakis (Greece)
   
12:45 13:30  Meet the Expert 26 - Repeated
Location: Hall B
12:45MTE26PCOS
E. Diamanti-Kandarakis (Greece)
   
12:45 13:30  Meet the Expert 27 - Repeated
Location: Hall C
12:45MTE27Differential diagnosis of Cushing's syndrome
J. Salvadore (Spain)
   
12:45 13:30  Meet the Expert 28 - Repeated
Location: Hall D
12:45MTE28Hypoglycaemia and diabetes management
W. Sheu (Taiwan)
   
12:45 13:30  Meet the Expert 29 - Repeated
Location: Hall E
12:45MTE29Management of bone loss induced by cancer treatment in early breast and prostate cancer
J. Body (Belgium)
   
12:45 13:30  Meet the Expert 30 - Repeated
Location: Hall F
12:45MTE30Treatment of vitamin D deficiency
N. Tandon (India)
   
12:45 13:30  Meet the Expert 31 - Repeated
Location: Hall G
12:45MTE31Cryptorchidism
J. Toppari (Finland)
   
12:45 13:30  Meet the Expert 32 - Repeated
Location: Hall H
12:45MTE32Management of GEP-NET tumours
K. Oberg (Sweden)
   
13:40 14:25  Plenary Lecture 8
Location: Main Hall
Chair: Chair(s): M. Mclean (Australia)
13:40PL8Novel molecular link between the circadian clock and hypertension
H. Okamura (Japan)
   
14:25 14:30  Farewell & Invitation to ECE 2013 Copenhagen
J. Castaňo (Spain) & J. Christiansen (Denmark)
Location: Main Hall
14:30   Post Congress Courses / Post Congress Industry Sponsored Satellite Symposia